Given how many times it has happened, it should not be a surprise that we are dealing with another fresh SARS-COV-2 podvariant, a virus responsible for Covid.
This fresh subvariant is known as XFG (called “Stratus“) And World Health Organization (Who) appointed this “monitoring variant” at the end of June. XFG is a subvariant of the omikron, which they are now Over 1000.
“Variant under monitoring” means a variant or subvariant which Priority needs comments and monitoring due to the features that can be an additional threat compared to other circulating variants.
XFG was one of the Seven variants in monitoring On June 25. The latest addition before XFG was NB.1.8.1 (called “Nimbus”), which he announced and WHO announced Variant in monitoring May 23.
Both nimbus and stratus are Types of clouds.
Nimbus is Currently dominant subvariant All over the world – but Stratus is approaching. So what do you need to know about Stratus or XFG?
Recombinant variant
XFG is Recombinator LF.7 and LP.8.1.2 Which means that these two fakes divide the genetic material that came up with a fresh subvariant. Recombinants are marked X at the beginning of their name.
While recombination and other instinctive changes often occur in the case of SARS-COV-2, this becomes a problem when it creates a podvariant who is changed in such a way that its properties cause more problems for us.
Most often this means that the virus looks different enough, that protection against previous infection (and vaccination) It doesn’t work so wellcalled Immune avoidance. Basically, this means that the population becomes more susceptible and can lead to an boost in cases, and even a completely fresh wave of Covid infections around the world.
XFG has Four key mutations In the spike protein, the protein on the surface of SARS-COV-2, which allows it to tie to our cells. It is believed that some boost the avoidance of some antibodies.
Early Laboratory tests I suggested Reduction almost twice In how well the antibodies block the virus compared to LP.8.1.1.
Where does XFG spread?
The earliest XFG sample was collected January 27.
On June 22, they existed 1 648 XFG sequences submitted to Gisaid from 38 countries (Gisaid It is a global database used to track the spread of various variants around the world). This accounts for 22.7% of the world sequences available worldwide at that time.
It was significant Increase with 7.4% Four weeks earlier and only just below the percentage of nb.1.8.1 at 24.9%. Considering that the generally falling percentage of viral sequences Nb.1.8.1 and rapid XFG growth, it seems reasonable expectation that XFG is soon dominating.
According to the Australian data expert, Mike Honey countries showing the highest XFG detection indicators from mid -June cover India in the amount of over 50%, followed by Spain at 42%, and Great Britain and the United States, in which the administration accounts for over 30%of cases.
In Australia, from June 29, nb.1.8.1 was the dominant podvariant, accounting 48.6% of the sequence. In the latest report from Australia National Genomic supervision platformOver the past 28 days, 24 XFG sequences have been collected, which means that it currently contains about 5% of the sequence.
Great questions
When we talk about the fresh Podvariant, people often ask questions, in whether it is more grave or cause fresh or various symptoms compared to previous variants. But we are still learning about XFG and we can not yet answer these questions.
Some sources have reported that XFG may be more exposed to “hoarseness” or Outlined or hoarse voice. However, we need more information to know if this association is really significant.
In particular, there is no evidence suggesting the causes of XFG more serious disease Compared to other variants in the circulation or that it is necessarily more transmitted.
Will vaccines still work against XFG?
Relatively regular virus changes mean that we are still updating Covid vaccines. The latest update, which is addressed to Subvariant Jn.1, has become available in Australia From the end of 2024. XFG is a descendant of Subvariant Jn.1.
Fortunately, based on the evidence available so far, Covid vaccines are currently approved stay effective against XFG, especially against symptomatic and grave illness.
Due to the further evolution of SARS-COV-2, the impact of this on our immune response, as well as actual protection against Covid vaccines with time, Covid vaccines are offered regularly and recommended for people at the highest risk.
One of the main challenges we are currently facing in Australia is to download low Covid vaccines. While the rates have increased slightly recently, they remain relatively low, with Only 32.3% of people Over the past six months at the age of 75 and more after receiving the vaccine. Vaccination indicators in younger age groups are much lower.
Although the situation with XFG must still be monitored, currently WHO has assessed the global risk posed by this subvariant as low. Covid control tips are unchanged, including vaccination as recommended and early Administering antiviral drugs For those who qualify.
Measures reduce the risk of transmissionEspecially wearing masks in crowded rooms in rooms and focusing on air quality and ventilation, it’s worth remembering protect against Covid and other viral infections.