African women exposed to a higher preeclama risk-sometimes secure pregnancy complication

Primer It is a danger for pregnant women. This is a complication characterized by high blood pressure and damage to the organs, arising in the second half of pregnancy, delivery or in the first week after delivery.

Plays an essential role in the area 16% death of pregnant women in Sub -Saharan Africa.

And increases: in the years 2010–2018 the incidence of preeclampsia in Africa jumped around 20%.

Przedkomltura usually occurs in juvenile mothers during the first pregnancy. Girls under the age of 18 are the most threatened. The probability that a 15-year-old girl will die due to pregnancy complications is one in 150 in developing countries, compared to one in 3800 in developed countries, in accordance with World Health Organization.

Pre-celampsia is not only a sedate threat to women’s health, but also harms children. Contributes to delivery, premature birth and low birth weight.

However, we still do not know enough about the front. This gap led my disease in my illness.

I conducted The first genetic test of case control on the theme of African women in Comparison of European women over ten years ago to my doctoral research.

My job revealed that both African and European populations have a gene (KIR AA genotype), which increases the chance of a preset. However, African women are greater risk Reveys than other racial groups. This is due to the fact that they are more exposed to wearing the fetus with the HLA-C C2 type C2 gene. African populations have a higher frequency of this gene, which increases the likelihood of risky mother-Fet combinations.

An additional discovery from my research is that genetic protection against the presence works differently between populations-A African populations carry unique protective genes. However, even with these additional protections, African women are more exposed to the development of bulky preeclampsia due to other challenges, such as access to healthcare and socio-economic restrictions.

There is unevenness in the treatment of the state. In my experience, wealthier and better developed African women often receive the necessary diagnosis and treatment. Too often, poorer and less educated African women do not.

Peuterrial tests, especially in Africa, require much greater financing, as well as broader research related to the health of African mothers of women.

Przaskultur in Uganda

Around 287,000 women The world dies during pregnancy and childbirth each year. Impossibly, 70% of them If African women.

Most of these deaths can be prevented. For example, around 10% They are the result of conditions associated with high blood pressure during pregnancy.

Ministry of Health in Uganda registered in 2023. 1,276 mothers’ deaths were reported 16% They were associated with high blood pressure.

Hospitals are overwhelmed by patients with illness. For example, National hospital recommending coffee In Kampala, he receives about 150 patients with this condition every month. He established a special branch for their treatment.

. Mothers mortality rate (Death due to complications of pregnancy or childbirth) in Uganda is 284 out of 100,000 live births. In Australia it is 2.94. Tumor Mortality rate (Death in the first 28 finished days of life) is 19 out of 1000 live births in Uganda against 2.37 in Australia. Infant mortality (death from a child) is 31 out of 1000 live births in Uganda compared to 3.7 in Australia, in accordance with Who’s Global Health Observatory.

This clear contrast emphasizes the huge gap in the care that pregnant mothers and children of both countries receive.

Part of the problem in Uganda, as in many developing countries, are indefinite challenges in healthcare infrastructure. Deficiency of healthcare professionals, medical articles and objects, especially in rural areas.

Early detection is key

As a clinician and researcher working at the Uganda Health Care Center, I am witnessing mothers coming to hospitals already in Critical conditionwith confined treatment options related to preeclampsia. This is painful.

The condition can be both prevented and subject to treatment if it is caught early. My tests It focuses on the identification of biological signs of the probability of complications during pregnancy, using data analysis based on artificial intelligence.

These predictive biomarkers, as they are called, allow us to categorize patients based on their risk levels and identify those who will most likely benefit from specific methods of treatment or preventive measures.

The exact causes of the frontal tube are not certain, but it is believed that factors that go beyond genetics are problems with the immune system and the inadequate development of the placenta. But many of what researchers know come from work done in high -income countries, often with confined attempts of African women.

Therefore, the findings may not apply directly to the genetics of African sub -Saharan women. My research relates to this difference in knowledge.

Based on my arrangements on genetic determinants, I run a research team at the University of Makerere to design interventions adapted to specific strategies for prevention and treatment for African populations.

Raising preeclastic awareness

The tests themselves are not enough. There is an urgent need to fill the gap between research and practice.

While working in the field, I was a first -hand witness, how many women in Uganda are not aware of the preventive warning signs and missed essential prenatal care. These warning signs often include headache, visual impairment, upper pain on the right of the abdomen and swelling of the legs.

However, we can develop screening algorithms so that healthcare employees can quickly diagnose women with a higher risk at an early stage of pregnancy. Timely intervention, including specific treatment and delivery plans, would reduce the risk of negative results for both mother and child.

As a domestic preeclampsia appointed by the Uganda Ministry, I manage initiatives to escalate awareness and improve access to mother’s healthcare services.

Through social assistance programs and educational campaigns, we want to strengthen all women, prosperous and indigent, knowing about their state and encourage them to seek medical assistance at an early stage.

More resources for genetic tests should be allocated to achieve our prevention goals, early detection, diagnosis and preeclable treatment and related complications.

This investment will escalate the development of predictive technology for precise diagnosis and will allow timely intervention to endangered mothers.

In addition, examining the genetic pre -monmatic roots can lead to fresh therapies that reduce the need for exorbitant medical procedures or long -term care for people affected by affected people.

This would reduce the burden of already overloaded African healthcare systems.